I was diagnosed with endometrial hyperplasia, atypia

By <name>/u/sdcinvan</name><uri>https://old.reddit.com/user/sdcinvan</uri>

Hello, I fully understand that advice from anyone online is not medical advice . Rather, I’m looking for informed opinions, personal experiences, and ideally references to reputable research. I think what I’m really looking for is either confirmation that my concerns are reasonable, or reassurance that I may be overthinking my concerns. I was just diagnosed with endometrial hyperplasia, atypia, and my gynaecologist has recommended a hysterectomy as soon as possible. She will be calling me next Monday to discuss the surgery and make the necessary arrangements. That reality is acceptable by me. In the meantime, I have been prescribed medroxyprogesterone acetate 40 mg per day. This dosage concerns me because I have coronary artery disease and underwent a double coronary bypass in 2018 after a 100% LAD blockage. I currently take low-dose aspirin, candesartan, rosuvastatin and ezetimibe. I understand why progesterone is being used for atypical hyperplasia, while I wait for surgery. What concerns me is that medroxyprogesterone carries warnings regarding blood clots and cardiovascular events, and 40 mg/day seems like a substantial dose. I’m having difficulty finding information specifically about medroxyprogesterone used in women who already have established coronary artery disease or a history of bypass surgery. Much of the cardiovascular research I’ve found involves estrogen combined with a progestin, which isn’t quite the same situation. Does anyone know of good research addressing the thromboembolic or cardiovascular risk of medroxyprogesterone alone in women with pre-existing coronary artery disease, particularly at higher doses? The timing is what makes this difficult. I’ve been instructed to begin the medication today, but I won’t be able to speak with my gynaecologist again until Monday. ---- On a different but related topic, I am also considering having my uterus, cervix and fallopian tubes removed while retaining my ovaries, if medically appropriate. I would be i

This headline was gathered automatically from a public feed. I AM GRACE does not host the full article — you will be taken to the original publisher.